Researchers from Mount Sinai School of Medicine in New York tested the effectiveness of a combination of cognitive-behavioral therapy and hypnosis (CBTH) to ameliorate radiotherapy-related fatigue.

Women (n = 42) scheduled for breast cancer radiotherapy were randomly assigned to receive standard medical care (SMC) (n = 20) or a CBTH intervention (n = 22) in addition to standard medical care.
 
Participants assigned to receive CBTH met individually with a clinical psychologist, receiving training in hypnosis and CBT. Participants assigned to the SMC control condition did not meet with a study psychologist.

Researchers from the University of Wisconsin School of Nursing in Madison evaluated the feasibility and potential efficacy of a patient-controlled cognitive-behavioral intervention for pain, fatigue, and sleep disturbance, during treatment for advanced cancer.  

This one group pre- and post-test design consisted of 30 adults with advanced (recurrent or metastatic) colorectal, lung, prostate, or gynecologic cancer receiving chemotherapy or radiotherapy.

Participants completed baseline measures (demographics and symptom inventory) and received education and training to use an MP3 player loaded with 12 cognitive-behavioral strategies (e.g., relaxation exercises, guided imagery, nature sound recordings, etc).

Researchers from the College of Nursing, Wayne State University in Detroit looked at who uses CAM practices (Complementary & Alternative medicine or the preferred term these days: Integrative Medicine) among survivors in the U.S. cancer population.
 
The study used the 2002 National Health Interview Survey (NHIS), with a sample of 2,262 adults (aged 18 years and older) diagnosed with cancer, representing more than 14.3 million cancer survivors in the United States .

Researchers from the Tom Baker Cancer Centre in Alberta, Calgary, investigated the effects of a mindfulness-based stress reduction (MBSR) meditation program on early stage breast and prostate cancer patients, examining quality of life, mood states, stress symptoms, as well as levels of cortisol, dehydroepiandrosterone-sulfate (DHEAS) and melatonin.

Fifty-nine patients with breast cancer and 10 with prostate cancer enrolled in an eight-week Mindfulness-Based Stress Reduction (MBSR) program that incorporated relaxation, meditation, gentle yoga, and daily home practice. Data was collected on demographic and health behavior variables, along with measures of quality of life, mood, stress, and assays of salivary cortisol (assessed three times/day), plasma DHEAS, and salivary melatonin, both pre- and post-intervention. 

Investigators from Mind Matters Research in Anchorage, Alaska summarized their Phase I National Cancer Institute (NCI)-funded clinical trial with 34 breast cancer survivors, six weeks to one year post-treatment, who were recruited to participate in a 6-class, 8-week long imagery stress reduction program entitled "Envision the Rhythms of Life."

Patients practiced imagery during and between sessions. Outcomes for quality of life and cortisol rhythm were assessed pre- to post-intervention, in two subsets of survivors (intravenous [IV] chemotherapy, or no IV chemotherapy).

Researchers from United Lincolnshire Hospitals and Queen's Medical Centre in the UK  performed a randomized, controlled trial to evaluate the immuno-modulatory effects of relaxation training and guided imagery on 80 women with breast cancer.

Patients underwent chemotherapy followed by surgery, radiotherapy, and hormone therapy. Those in the intervention group were taught relaxation and guided imagery. Patients kept diaries of the frequency of relaxation practice and imagery vividness.

Researchers from the Niehoff School of Nursing, Loyola University of Chicago, used a non-randomized, controlled design to evaluate the effect and feasibility of a mindfulness based stress reduction (MBSR) program on immune function, quality of life (QOL), and coping in women newly diagnosed with breast cancer.

Early stage breast cancer patients, who did not receive chemotherapy, self-selected into an 8-week MBSR program or into an assessment-only control group. Outcomes were evaluated over time. The first assessment was at least 10 days after surgery and prior to adjuvant therapy, as well as before the MBSR start-up. Further assessments were mid-MBSR, at completion of MBSR, and at 4-week post-MBSR completion.