Cochrane analysts examined five randomized, controlled trials of the efficacy of exercise therapy for Chronic Fatigue Syndrome (CFS) and found that after 12 weeks, those receiving exercise therapy were less fatigued than the control participants (SMD -0.77, 95% CIs -1.26 to -0.28).  Additionally, physical functioning was significantly improved with exercise therapy (SMD -0.64, CIs -0.96 to -0.33) but there were more dropouts with exercise therapy (RR 1.73, CIs 0.92 to 3.24). 

Investigators from the Department of Medicine at the University of Washington in Seattle looked at patterns of alternative medicine use among twins where one twin of the pair had CFS and the other did not.  They also looked at the perceived helpfulness of these methods, and how often these therapies were discussed with physicians.

Just as the person who wrote in, I have been a chronic fatigue sufferer for eight long and lonely years.  This is not only distressing due to the chronic pain, exhaustion and interference with the ability to function normally on a daily basis.  It is also distressing because people don’t believe there is anything wrong with you and get impatient and angry. For years I had judgmental doctors who hated seeing me in the waiting room because they knew they could not help me and therefore blamed me for being sick, just like you wrote. I was told I was stressed and depressed.  That was definitely true, but this was because of my CFS, not what started it!!!!!!!!!!!!