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For Major Depression, Behavioral Therapies Out-do Meds |
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Monday, 03 November 2008 |
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 Romanian researchers from Babes-Bolyai University in Cluj, Romania, undertook a randomized clinical trial to investigate the relative efficacy of rational-emotive behavior therapy (REBT), cognitive therapy (CT), and pharmacotherapy in the treatment of 170 outpatients with nonpsychotic, major depressive disorder.
The patients were randomly assigned to one of the following: 14 weeks of REBT, 14 weeks of CT, or 14 weeks of pharmacotherapy (fluoxetine or prozac). The outcome measures used were the Hamilton Rating Scale for Depression and the Beck Depression Inventory.
No differences among treatment conditions at posttest were
observed. REBT had a larger and significant effect over the
medication, and CT had a less large effect over medication (a
nonsignificant one) at 6 months follow-up, on the Hamilton Rating
Scale for Depression only. Citation: David D, Szentagotai A,Lupu V, Cosman D. Rational emotive behavior therapy, cognitive therapy, and medication in the treatment of major depressive disorder: a randomized clinical trial, posttreatment outcomes, and six-month follow-up. Journal of Clinical Psychology. 2008 Jun; 64 (6): pages
728-46.
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